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| 3. |  | RIBEIRO, S. M.; ROSINHA, G. M. S.; SANTOS, L. R. dos; SANTOS, G. M. Avaliação da resposta imune de camundongos BALB/c a uma proteína recombinante visando o desenvolvimento de vacina contra tristeza parasitária bovina. In: JORNADA CIENTÍFICA EMBRAPA GADO DE CORTE, 11., 2015, Campo Grande, MS. Anais... Campo Grande: Embrapa Gado de Corte, 2015. 114 p. (Embrapa Gado de Corte. Documentos, 213).| Biblioteca(s): Embrapa Gado de Corte. |
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| 6. | | TONUCCI, L. B.; SANTOS, K. M. O. dos; OLIVEIRA, L. L. de; RIBEIRO, S. M. R.; MARTINO, H. S. D. Clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study. Clinical Nutrition, v. 36, n. 1, p. 85-92, 2017.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 10. | | FERREIRA, C. S. dos S.; LEMOS, W. de P.; RIBEIRO, S. M.; ARAÚJO, M. R. de; SILVA, L. C. da. Abundância de Solenopsis spp. (Westwood) (Hymenoptera: Formicidae) em diferentes sistemas de cultivo de açaí (Euterpe oleraceae Mart.) no nordeste paraense. In: SIMPÓSIO DE CONTROLE BIOLÓGICO, 13., 2013, Bonito, MS. Faça bonito: use controle biológico: anais. Brasília, DF: Embrapa, 2013. 1 CD-ROM.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| 11. | | RIBEIRO, S. M.; ROSINHA, G. M. S.; SOARES, C. O.; SANTOS, L. R. dos; GOMES, J. S. Análise da imunogenicidade de uma proteína recombiante em camundongos BALB/c visando o desenvolvimento de vacina contra tristeza parasitária bovina. In: SIMPÓSIO DE IMUNOLOGIA DO CENTRO-OESTE, I., Goiânia, 2017. Revista de Patologia Tropical, v. 46, supl. 1, p. 16, 2017.| Biblioteca(s): Embrapa Gado de Corte. |
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| 12. | | OLIVEIRA, T. A. de; RIBEIRO, S. M.; ARAÚJO, M. R. de; SILVA, L. C. da; LEMOS, W. de P. Artrópodes predadores de solo em diferentes sistemas de cultivo de açaí nos municípios de Igarapé-açu e Marapanim, PA. In: SIMPÓSIO DE CONTROLE BIOLÓGICO, 13., 2013, Bonito, MS. Faça bonito: use controle biológico: anais. Brasília, DF: Embrapa, 2013. 1 CD-ROM.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| 13. | | FERREIRA, C. S. dos S.; LEMOS, W. de P.; RIBEIRO, S. M.; ARAÚJO, M. R. de; SILVA, L. C. da. Assembleia de formigas predadoras em monocultivo de açaí Euterpe oleraceae Mart.) no município de Igarapé-Açu, Pará. In: SIMPÓSIO DE CONTROLE BIOLÓGICO, 13., 2013, Bonito, MS. Faça bonito: use controle biológico: anais. Brasília, DF: Embrapa, 2013. 1 CD-ROM.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| 14. | | SARDÁ, L. G.; GRAVE, R. A.; FALKOSKY, C.; RIBEIRO, S. M. S.; NICOLOSO, R. da S.; HIGARASHI, M. M. Global warming potential of three swine manure management systems used in Brazil. In: SIMPÓSIO INTERNACIONAL SOBRE GERENCIAMENTO DE RESÍDUOS AGROPECUÁRIOS E AGROINDUSTRIAIS, 4., 2015, Rio de Janeiro, RJ. Anais... Brasília: Embrapa, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 15. | | SARDÁ, L. G.; HIGARASHI, M. M.; NICOLOSO, R. da S.; FALKOSKI, C.; RIBEIRO, S. M. S.; SOARES, H. M. The influence of use additives on nitrous oxide emission during swine slurry composting. In: LATIN AMERICAN CONGRESS, 4., 2015, Florianópolis. Anais... Florianópolis: UFSC, 2015. Disponível on line. SOLABIAA.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 16. | | AQUINO, C. F.; SALOMÃO, L. C. C.; SIQUEIRA, D. L. de; CECON, P. R.; RIBEIRO, S. M. R. Teores de minerais em polpas e cascas de frutos de cultivares de bananeira. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 49, n. 7, p. 546-553, jul. 2014. Título em inglês: Mineral content in the pulp and peel of banana cultivars.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 19. | | SILVA, L. C. da; RIBEIRO, S. M.; LEMOS, W. de P.; OLIVEIRA, T. A. de; FRANÇA, L. P. N.; ARAUJO, M. R. de. Artropodofauna edáfica associada a cultivos de açaí (Euterpe oleraceae) em municípios do Nordeste paraense. In: SEMINÁRIO ANUAL DE INICIAÇÃO CIENTÍFICA DA UFRA, 12., 2014, Belém, PA. Anais. Belém, PA: Universidade Federal Rural da Amazônia, 2014.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| 20. | | LISBÔA, M. A. A. T.; OLIVEIRA, J. S. F. de; SILVA, R. de M.; SILVA, J. L. C.; RIBEIRO, S. M.; CARVALHO, E. de A. Monitoramento da ferrugem asiática da soja no estado do Pará. In: CONFERÊNCIA NACIONAL SOBRE DEFESA AGROPECUÁRIA, 4., 2013, Belém, PA. Defesa agropecuária e sustentabilidade. Belém, PA: SBDA, 2014. p. 167-168.| Biblioteca(s): Embrapa Amazônia Oriental. |
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| Registros recuperados : 37 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agroindústria de Alimentos. Para informações adicionais entre em contato com ctaa.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
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Data corrente: |
02/12/2016 |
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Data da última atualização: |
25/09/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
TONUCCI, L. B.; SANTOS, K. M. O. dos; OLIVEIRA, L. L. de; RIBEIRO, S. M. R.; MARTINO, H. S. D. |
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Afiliação: |
Livia Bordalo Tonucci, INTA; KARINA MARIA OLBRICH DOS SANTOS, CTAA; Leandro Licursi de Oliveira, UFV; Sonia Machado Rocha Ribeiro, UFV; Hercia Stampini Duarte Martino, UFV. |
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Título: |
Clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Clinical Nutrition, v. 36, n. 1, p. 85-92, 2017. |
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DOI: |
10.1016/j.clnu.2015.11.011. |
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Idioma: |
Inglês |
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Conteúdo: |
Background & aims: Type 2 diabetes has been associated with dysbiosis and one of the possible routes to restore a healthy gut microbiota is by the regular ingestion of probiotics. We aimed to investigate the effects of probiotics on glycemic control, lipid profile, inflammation, oxidative stress and short chain fatty acids in T2D. Methods: In a double-blind, randomized, placebo-controlled trial, 50 volunteers consumed daily 120 g/d of fermented milk for 6 wk. Participants were assigned into two groups: probiotic group, consuming fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp lactis BB-12 (109 colony-forming units/d, each) and control group, consuming conventional fermented milk. Anthropometric measurements, body composition, fasting blood and faecal samples were taken at baseline and after 6 wk. Results: 45 subjects out of 50 (90%) completed follow-up. After 6 wk, there was a significant decrease in fructosamine levels (9.91 mmol/L; p ¼ 0.04) and hemoglobin A1c tended to be lower (0.67%; p ¼ 0.06) in probiotic group. TNF-a and resistin were significantly reduced in probiotic and control groups (1.5 and 1.3 pg/mL, .1 and 2.8 ng/mL, respectively), while IL-10 was significantly reduced ( 0.65 pg/mL; p < 0.001) only in the control group. Fecal acetic acid was increased in both groups (0.58 and 0.59% in probiotic and control groups, respectively; p < 0.01). There was a significant difference between groups concerning mean changes of HbA1c (þ0.31 for control group vs 0.65 for probiotic group; p ¼ 0.02), total cholesterol (þ0.55 for control group vs 0.15 for probiotic group; p ¼ 0.04) and LDL-cholesterol (þ0.36 for control group vs 0.20 for probiotic group p ¼ 0.03). Conclusions: Probiotic consumption improved the glycemic control in T2D subjects, however, the intake of fermented milk seems to be involved with others metabolic changes, such as decrease in inflammatory cytokines (TNF-a and resistin) and increase in the acetic acid. MenosBackground & aims: Type 2 diabetes has been associated with dysbiosis and one of the possible routes to restore a healthy gut microbiota is by the regular ingestion of probiotics. We aimed to investigate the effects of probiotics on glycemic control, lipid profile, inflammation, oxidative stress and short chain fatty acids in T2D. Methods: In a double-blind, randomized, placebo-controlled trial, 50 volunteers consumed daily 120 g/d of fermented milk for 6 wk. Participants were assigned into two groups: probiotic group, consuming fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp lactis BB-12 (109 colony-forming units/d, each) and control group, consuming conventional fermented milk. Anthropometric measurements, body composition, fasting blood and faecal samples were taken at baseline and after 6 wk. Results: 45 subjects out of 50 (90%) completed follow-up. After 6 wk, there was a significant decrease in fructosamine levels (9.91 mmol/L; p ¼ 0.04) and hemoglobin A1c tended to be lower (0.67%; p ¼ 0.06) in probiotic group. TNF-a and resistin were significantly reduced in probiotic and control groups (1.5 and 1.3 pg/mL, .1 and 2.8 ng/mL, respectively), while IL-10 was significantly reduced ( 0.65 pg/mL; p < 0.001) only in the control group. Fecal acetic acid was increased in both groups (0.58 and 0.59% in probiotic and control groups, respectively; p < 0.01). There was a significant difference between groups concerning mean changes of Hb... Mostrar Tudo |
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Palavras-Chave: |
Gut microbiota; Oxidative; Type 2 diabetes. |
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Thesagro: |
Stress. |
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Thesaurus NAL: |
inflammation; probiotics. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02784naa a2200253 a 4500
001 2057801
005 2017-09-25
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1016/j.clnu.2015.11.011.$2DOI
100 1 $aTONUCCI, L. B.
245 $aClinical application of probiotics in type 2 diabetes mellitus$ba randomized, double-blind, placebo-controlled study.$h[electronic resource]
260 $c2017
520 $aBackground & aims: Type 2 diabetes has been associated with dysbiosis and one of the possible routes to restore a healthy gut microbiota is by the regular ingestion of probiotics. We aimed to investigate the effects of probiotics on glycemic control, lipid profile, inflammation, oxidative stress and short chain fatty acids in T2D. Methods: In a double-blind, randomized, placebo-controlled trial, 50 volunteers consumed daily 120 g/d of fermented milk for 6 wk. Participants were assigned into two groups: probiotic group, consuming fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp lactis BB-12 (109 colony-forming units/d, each) and control group, consuming conventional fermented milk. Anthropometric measurements, body composition, fasting blood and faecal samples were taken at baseline and after 6 wk. Results: 45 subjects out of 50 (90%) completed follow-up. After 6 wk, there was a significant decrease in fructosamine levels (9.91 mmol/L; p ¼ 0.04) and hemoglobin A1c tended to be lower (0.67%; p ¼ 0.06) in probiotic group. TNF-a and resistin were significantly reduced in probiotic and control groups (1.5 and 1.3 pg/mL, .1 and 2.8 ng/mL, respectively), while IL-10 was significantly reduced ( 0.65 pg/mL; p < 0.001) only in the control group. Fecal acetic acid was increased in both groups (0.58 and 0.59% in probiotic and control groups, respectively; p < 0.01). There was a significant difference between groups concerning mean changes of HbA1c (þ0.31 for control group vs 0.65 for probiotic group; p ¼ 0.02), total cholesterol (þ0.55 for control group vs 0.15 for probiotic group; p ¼ 0.04) and LDL-cholesterol (þ0.36 for control group vs 0.20 for probiotic group p ¼ 0.03). Conclusions: Probiotic consumption improved the glycemic control in T2D subjects, however, the intake of fermented milk seems to be involved with others metabolic changes, such as decrease in inflammatory cytokines (TNF-a and resistin) and increase in the acetic acid.
650 $ainflammation
650 $aprobiotics
650 $aStress
653 $aGut microbiota
653 $aOxidative
653 $aType 2 diabetes
700 1 $aSANTOS, K. M. O. dos
700 1 $aOLIVEIRA, L. L. de
700 1 $aRIBEIRO, S. M. R.
700 1 $aMARTINO, H. S. D.
773 $tClinical Nutrition$gv. 36, n. 1, p. 85-92, 2017.
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